
Spokes and nipples are next. Aluminium nipples save approximately 20 grams per 32 spokes and significant savings can be made with light spokes like DT's Revolution and Aerospeed and Sapim's Laser and CX-Ray types.
Hubs are next and to make any real savings there, the choice would have to be from smaller manufacturers who make Shimano and/or Campag compatible options that are lighter than the big names. The current lightweight champs are American Classic at 275 grams the pair weighed without skewers. Many rear hubs weigh this much and more on their own. They are available in both Campag and Shimano compatible versions.
Significant savings can be made with titanium or aluminium cassette stacks but they cost, particularly titanium, and don't wear as well as the steel cogs more commonly available. As mentioned earlier though; everything on your bike has to be carted up the hills you choose to ride. Any weight saving is helpful if it doesn't compromise safety or comfort, but weight saved at the periphery of a wheel is more beneficial than weight saved at the centre of a wheel or elsewhere on a bike.
The other thing that needs to be mentioned is that light wheels certainly help a rider climb hills but quicken steering response when descending because of reduced gyroscopic forces. This can catch some unawares.
With the rest of the bike, many components can be exchanged for lighter versions but the caution here is best summed up by 'light, durable, cheap; pick any two (I don't know who said that but it is on the money) While wheels are the most important area where weight can be saved, anything that rotates is next in line which means pedals, cranks and bottom brackets.
Lightweight pre built wheels are another option and are available from a variety of manufacturers including Zipp, Mavic, Campagnolo, Fulcrum, Shimano, American Classic and others. With the exception of Zipp. Many of the commonly available pre built wheel weigh within 50 grams either side of 1500 grams without skewers, but American Classic make a budget model that weighs less than 1400 grams and Zipp have some extraordinarily light wheels that can in some configurations come in at around the 1000 gram mark.
Don't discount aero rims for hill climbing providing you can find light ones. At the moment this means carbon. I was reading some wind tunnel data the other day which suggests that on moderate grades riders with good power outputs can still gain an advantage with light aero wheels through reduced aerodynamic drag. Unfortunately on steeper grades where speed drops, this advantage almost disappears.
One potential concern with aero rims is when riding at speed on descents. An aero front rim can catch a lot a lot or wind and can in strong sidewinds cause a few heart in mouth moments. It is advisable to ride a lower profile rim on the front if you choose to go the light aero route
Lastly, I see more than a few riders who can just about recite a list of component weights from www.weightweenies.com but carry 5kg more ballast around their middles than they need to. Losing that extra weight will improve performance at least much as any equipment changes you make.